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Cancer Research: What is the sensitivity and specificity of the BRCA1 and 2 mutations?
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In general, yes it is safe. But there are exceptions based on the conditions. A woman who is developing breast cancer might be excreting small amounts of fluids from the nipples. A woman who is lactating (to feed babies) is also ‘leaking’ fluids. Now, whenever a fluid is exchanged between two bod....
As you know, chemotherapy, radiation and surgery, along with targeted treatments, gene therapy, laser and a few others are the standard traditional procedures for cancer treatment; they are called that because they have a proven track record and you can look up research results and find out that tho....
It depends on the country. Overdiagnosis relates to the finding of a cancer that doesn’t act in a life-limiting way. Since the beginning of mammography and PSA eras we have diagnosed a lot of such disease.Mammography has not changed the percentage of women who have metastatic disease, rather it has ....
Nidii Berwal
Genes and genetic variations in our body contribute to the bodily functions and overall health. This also includes the possibility of having various diseases which are hereditary or developed in our body due to changes in the genetic codes. BRCA -1 & BRCA – 2 are two genes which are linked to Hereditary Breast and Ovarian Cancer. These genes produce tumor suppressor proteins which help to repair damaged DNA. When either of these genes have mutations, it increases the risk of cancer. BRCA 1 & BRCA 2 testing should be considered if: You had breast cancer at early age Your mother, sister, or daughter had breast cancer at early age or ovarian cancer. You are a woman with 1st degree relative who’s diagnosed with bilateral breast cancer before age of 50 The men in your family have strong history of breast/ ovarian cancer. Women who have BRCA 1 gene mutation are at higher risk of triple negative breast cancer while BRCA 2 carriers have breast cancers that are Estrogen Receptor positive. BRCA 1/2 mutations increase the risk of ovarian cancer.