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By serum keratin you mean serum creatinine. Right? And WBC of 16000 is definitely high and with all those symptoms say he would also have high grade fever. He needs to visit an internal medicine specialist and get tested for any renal disease. High creatinine means renal disease and since he already has diabetes and heart problems, this should not be ignored. Let us know your city so that we can get you in touch with the best internal medicine/ urologist at the earliest.