0
Cancer Research: What is the sensitivity and specificity of the BRCA1 and 2 mutations?
- 1 people answered
0 Vote
1 Contributor
1784 Views 
0 Saved
0 Vote 1 Contributor1784 Views 0 SavedYou might also be interested in
Yes, radiotherapy or radiation treatment can cause side effects. The effects may appear after a couple of weeks of treatment. They continue to get even worse during the treatment and after the treatment has finished. However, A few weeks after treatment things start to get better. Everyone is diffe....
Don’t worry, most breast cysts can be very small and will only show up on ultrasound scans, and these are termed microcysts. About 25% of breast cysts enlarge gradually into ‘big-enough’ cysts to become a palpable breast lump. Breast cysts are extremely common, and occur in as many as one third of ....
Study findings on a potential link between breast size and breast cancer have been mixed. Some studies have found having a larger breast size increases risk, while others have found no link between breast size and risk but few studies have suggested that breast size increases risk among thin women,....
Nidii Berwal
Genes and genetic variations in our body contribute to the bodily functions and overall health. This also includes the possibility of having various diseases which are hereditary or developed in our body due to changes in the genetic codes. BRCA -1 & BRCA – 2 are two genes which are linked to Hereditary Breast and Ovarian Cancer. These genes produce tumor suppressor proteins which help to repair damaged DNA. When either of these genes have mutations, it increases the risk of cancer. BRCA 1 & BRCA 2 testing should be considered if: You had breast cancer at early age Your mother, sister, or daughter had breast cancer at early age or ovarian cancer. You are a woman with 1st degree relative who’s diagnosed with bilateral breast cancer before age of 50 The men in your family have strong history of breast/ ovarian cancer. Women who have BRCA 1 gene mutation are at higher risk of triple negative breast cancer while BRCA 2 carriers have breast cancers that are Estrogen Receptor positive. BRCA 1/2 mutations increase the risk of ovarian cancer.