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Why does gluconeogenesis occur just in the liver and a few other tissues?
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Sir do ur hospital do treatment for liver jondis
The portal vein is responsible for transports cholesterol in chylomicrons from the intestine to the liver. Chylomicrons are tiny balls that enclose fatty particles like cholesterol. The hepatic portal vein is one of the most important veins that helps in receiving blood from the body and transports ....
Liver cells or hepatocytes have glucagon receptors. Glucagon can easily target the liver. When glucagon binds to the glucagon receptors it is then converted into individual glucose molecules by liver cell and release them into the bloodstream. This process is known as glycogenolysis. Glucagon afterw....
Mithun Kumar
Gluconeogenesis is a metabolic process that results in the generation of glucose from non-carbohydrate carbon substrates like lactate, glycerol, and glycogenic amino acids. Liver cells or hepatocytes have glucagon receptors. Gluconeogenesis occurs in the kidneys and only in the liver. This is due to the fact that the liver has evolved to be the seat of metabolism in our bodies. Its primary function among others is to maintain a steady blood glucose level especially in the brain which cannot use any other source of fuel. Since the liver has evolved to be the seat of metabolism it makes sense for it to express the genes for gluconeogenesis and its regulation to perform its function rather than say the brain which needs to spend energy for its various functions.