2
Why does the liver enlarge in thalassemia?
- 1 people answered
3 Votes
1 Contributor
3352 Views 
0 Saved
3 Votes 1 Contributor3352 Views 0 SavedYou might also be interested in
When a sonographic examination of your liver is done, the texture of the liver is highlighted. A normal liver's texture is uniform/ smooth. When the surface of the liver is irregular/ not uniform i.e. the liver parenchyma is irregular, it indicates some form of liver disease. Incase your reports ind....
Diseases which cause both an enlarged liver and psychosis are some Cancers like Some types of leukaemia, lymphoma, Multiple myeloma and some genetic diseases like Hemochromatosis, Wilson's disease, Glycogen storage diseases, Gaucher's disease. Along with this Porphyria also causes both enlarged live....
A healthy liver helps the body in fighting infections, blood problems, can repair itself when damaged and is important in metabolism. If our liver does not work properly, it can cause various issues even life-threatening one. So, it is important to find out the cause of pain and to get treatment to ....
Akanksha Pardeshi
The enlargement of Liver happens due to continuous transfusions without adequate chelation.
If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelation. Is the case of thalassemia, organs are expanding due to the dual effects of low hemoglobin in the body. In some cases, the bone marrow can produce some amount of misshaped RBCs.
The Spleen then becomes hyperactive to get rid of these cells, which in turn leads to the bone marrow trying to work some more - in effect, a vicious cycle develops where the spleen will get enlarged and the bone marrow will expand, weakening the bones. The only key to Success over Thalassemia is Adequate Transfusion with Adequate Chelation without worrying about future.