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Why does the liver regenerate itself?
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Dr Thomas Starzl was the first surgeon who transplanted liver. He died at the age of 90years. The first attempt was performed in 1963 but the patient died due to uncontrolled bleeding. Until 1967 multiple unsuccessful attempts were made by various surgeons. In 1967 Dr Thomas transplanted liver of ni....
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Anamika Sharma
The liver is the only organ in the living being which has the capability to regenerate after injury and surgeries. In mammals only mass of liver is replaced but not shape therefore the process of regeneration is compensatory growth. But in lower size species both shape and size can be replaced. The liver regeneration is due to replication of liver cell which follows the removal of tissue (partial hepatectomy) and enlargement of hepatocytes followed by proliferation of hepatocyte. They are also capable of transdifferentiating into other cell types such those of the biliary system. The liver is the main site of drug detoxification. It is exposed to many chemicals in the body which may lead to cell death and injury. Thus the liver can regenerate damaged tissue rapidly preventing damage. This ability of the liver to regenerate is called homeostasis.