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Why does the liver regenerate itself?
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Liver cells or hepatocytes have glucagon receptors. Glucagon can easily target the liver. When glucagon binds to the glucagon receptors it is then converted into individual glucose molecules by liver cell and release them into the bloodstream. This process is known as glycogenolysis. Glucagon afterw....
Liver sinusoidal endothelial cells are constituted of a sinusoidal wall which is also called as endothelium or endothelial lining. The liver sinusoids are unique capillaries because of the presence of open pores or fenestrae lacking a diaphragm and a basal lamina underneath the endothelium, which di....
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Anamika Sharma
The liver is the only organ in the living being which has the capability to regenerate after injury and surgeries. In mammals only mass of liver is replaced but not shape therefore the process of regeneration is compensatory growth. But in lower size species both shape and size can be replaced. The liver regeneration is due to replication of liver cell which follows the removal of tissue (partial hepatectomy) and enlargement of hepatocytes followed by proliferation of hepatocyte. They are also capable of transdifferentiating into other cell types such those of the biliary system. The liver is the main site of drug detoxification. It is exposed to many chemicals in the body which may lead to cell death and injury. Thus the liver can regenerate damaged tissue rapidly preventing damage. This ability of the liver to regenerate is called homeostasis.