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Portal vein carries things away from the intestines and stomach & headed it to the liver because of which the liver receives regular blood from the artery & the intestines, which is headed from the gut to the liver for processing. These sources of blood drain from the liver in the hepatic ve....
The enlargement of Liver happens due to continuous transfusions without adequate chelation. If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelatio....
The liver plays an important role in the digestion. The reason for this is that when digested nutrients from the small intestine drain directly into veins which connect into the portal vein. Therefore these nutrients need to be filtered as a first stop before going to the rest of the organs. Blood f....
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The enlargement of Liver happens due to continuous transfusions without adequate chelation.
If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelation. Is the case of thalassemia, organs are expanding due to the dual effects of low hemoglobin in the body. In some cases, the bone marrow can produce some amount of misshaped RBCs.
The Spleen then becomes hyperactive to get rid of these cells, which in turn leads to the bone marrow trying to work some more - in effect, a vicious cycle develops where the spleen will get enlarged and the bone marrow will expand, weakening the bones. The only key to Success over Thalassemia is Adequate Transfusion with Adequate Chelation without worrying about future.