3 Votes
1 Contributor
94 Views
0 Saved
You might also be interested in
An increase in the SGOT and SGPT levels is an indication of liver damage. The normal level of 30 for males and 19 for females if it reaches it medical attention is required. SGPT levels in the blood are thus compared with liver damage for example, from viral hepatitis or with compared to the heart f....
The portal vein is responsible for transports cholesterol in chylomicrons from the intestine to the liver. Chylomicrons are tiny balls that enclose fatty particles like cholesterol. The hepatic portal vein is one of the most important veins that helps in receiving blood from the body and transports ....
Liver cells or hepatocytes have glucagon receptors. Glucagon can easily target the liver. When glucagon binds to the glucagon receptors it is then converted into individual glucose molecules by liver cell and release them into the bloodstream. This process is known as glycogenolysis. Glucagon afterw....
Receive guidance from the first consultation through the entire hospitalization process.
Medical experts assist the patients to find the right doctor and book appointments.
Consult with 5000+ doctors online and get all your health queries answered.
Dr. Akanksha Pardeshi
The enlargement of Liver happens due to continuous transfusions without adequate chelation.
If there is no chelation at all it will enlarge quickly and vice versa. So, Hepatomegaly does happen in Thalassemia because Liver stores the excess iron which remains in the body due to inadequate chelation. Is the case of thalassemia, organs are expanding due to the dual effects of low hemoglobin in the body. In some cases, the bone marrow can produce some amount of misshaped RBCs.
The Spleen then becomes hyperactive to get rid of these cells, which in turn leads to the bone marrow trying to work some more - in effect, a vicious cycle develops where the spleen will get enlarged and the bone marrow will expand, weakening the bones. The only key to Success over Thalassemia is Adequate Transfusion with Adequate Chelation without worrying about future.